Developed by Dr. Masanobu Satake, Tohoku University. C57BL/6 background. PTP rho, Protein tyrosine phospatase receptor type T, is a member of the receptor tyrosine phosphatase family. PTPs are signaling molecules that regulate a variety of cellular processes including mitotic cycle, cell growth, differentiation, and oncogenic transformation. At present, homozygous mutant mice show no abnormality. 佐竹 正延 E14.1 [129P2/OlaHsd] Masanobu SATAKE true C (3-6 months) 作製後、 B6/J (日本クレア) に 13 代バッククロスした。 <a href='https://brc.riken.jp/mus/pcr01489'>Genotyping protocol -PCR-</a> backcross to C57BL/6 (Heterozygote x C57BL/6J) 条件を付加する。利用者は事前に寄託者の提供承諾書を得る。<br><br>研究成果の公表にあたって謝辞の表明を必要とする。<br>共同研究として用い、寄託後2年間は論文や学会での発表の際は共著とする。寄託者の研究と競合する用途を避けるために、予定の研究概要を寄託者に知らせ、使用許可を得る。本件リソースの特許権ならびに知的所有権は寄託者が保持しており、利用者が本件リソースから得られた結果により特許等を申請する場合には事前に寄託者と別途協議する。 C(3〜6か月) Tohoku Univ. RBRC01489 The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. <br>In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to include the DEPOSITOR as a co-author in any publications resulted by the use of the BIOLOGICAL RESOURCE during the first 2 years after deposition by the DEPOSITOR to the RIKEN BRC.<br>The RECIPIENT should contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE. mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, pA, mouse PTP rho genomic DNA B6.129P2-Ptprt<tm1Sata>/SataRbrc B6.129P2-Ptprt<tm1Sata>/SataRbrc Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> 国立大学法人東北大学 PTP rho KO 231 PTP rho KO 231